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  Contents > Previous page > Article detail print Order
o Issue N# 5 - 2008 o

MAXILLO-FACIAL AND OHARYNGE

Solitary myofibroma of the mandible: A case report


Authors : Ech-Charif S, Benhammou A, Maher M, Séfiani S. (Rabat)

Ref. : Rev Laryngol Otol Rhinol. 2008;129,5:337-340.

Article published in french
Downloadable PDF document french



Summary : Objectives: Infantile myofibromatosis (IMF) are integrated in the group of fibromatosis juvenile-type which are benign mesenchymal lesions, characterized morphologicaly by a proliferation of fibroblasts and myofibroblastes, with perivascular pattern. Through a case of solitary myofibroma of the mandible, we will emphasize anatomo-clinical features and differential diagnosis. Materials and methods: We report a case illustrating solitary myofibroma of the mandible in 18 month old infant. Results: The histological diagnosis was done on the identification of two separate components, a fascicular myofibroblastic pattern at the periphery with a hemangiopericytoma like pattern in the centre. Both components positive for alpha-smooth muscle actin and vimentin. Discussion: Solitary IMF is characterised by a single lesion arising from cutaneous, bony or soft tissues. Morphological and immunohistochemical examination allow the diagnosis of the typical form. The differential diagnosis includes other benign spindle cells tumours. The prognosis is excellent with possibility to regress spontaneously.

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